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Minocycline-induced microbiome alterations predict cafeteria diet-induced spatial recognition memory impairments in rats

Diets rich in sugar and saturated fat are associated with cognitive impairments in both humans and rodents with several potential mechanisms proposed. To test the involvement of diet-induced pro-inflammatory signaling, we exposed rats to a high-fat, high-sugar cafeteria diet, and administered the an...

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Опубликовано в: :Transl Psychiatry
Главные авторы: Leigh, Sarah-Jane, Kaakoush, Nadeem O., Westbrook, R. Frederick, Morris, Margaret J.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069973/
https://ncbi.nlm.nih.gov/pubmed/32170156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-0774-1
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