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Dishevelled 1-Regulated Superpotent Cancer Stem Cells Mediate Wnt Heterogeneity and Tumor Progression in Hepatocellular Carcinoma

Various populations of cancer stem cells (CSCs) have been identified in hepatocellular carcinoma (HCC). Wnt signaling is variably activated in HCC and regulates CSCs and tumorigenesis. We explored cell-to-cell Wnt and stemness heterogeneity in HCC by labeling freshly isolated cancer cells with a Wnt...

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Publicat a:Stem Cell Reports
Autors principals: Liao, Wen-Ying, Hsu, Chung-Chi, Chan, Tze-Sian, Yen, Chia-Jui, Chen, Wei-Yu, Pan, Hung-Wei, Tsai, Kelvin K.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066362/
https://ncbi.nlm.nih.gov/pubmed/32160521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.02.003
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