BRD4 Inhibition by AZD5153 Promotes Antitumor Immunity via Depolarizing M2 Macrophages

High-grade serous ovarian cancer (HGSOC), with its high recurrence rates, urges for reasonable therapeutic strategies that can prolong overall survival. A tumor microenvironment (TME) discloses prognostic and prospective information on cancer, such as the expression level of PD-1 or PD-L1. However,...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Li, Xi, Fu, Yu, Yang, Bin, Guo, Ensong, Wu, Yifan, Huang, Jia, Zhang, Xiaoxiao, Xiao, Rourou, Li, Kezhen, Wang, Beibei, Hu, Junbo, Sun, Chaoyang, Chen, Gang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058627/
https://ncbi.nlm.nih.gov/pubmed/32184777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00089
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