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Therapeutic Targeting of CDK7 Suppresses Tumor Progression in Intrahepatic Cholangiocarcinoma

Intrahepatic cholangiocarcinoma (ICC) is a lethal malignancy with high mortality and lack of effective therapeutic targets. Here, we found that expression of cyclin-dependent kinase 7 (CDK7) was significantly associated with higher tumor grade and worse prognosis in 96 ICC specimens. Depletion of CD...

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Foilsithe in:Int J Biol Sci
Main Authors: Chen, Hua-Dong, Huang, Chen-Song, Xu, Qiong-Cong, Li, Fuxi, Huang, Xi-Tai, Wang, Jie-Qin, Li, Shi-Jin, Zhao, Wei, Yin, Xiao-Yu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Ivyspring International Publisher 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053328/
https://ncbi.nlm.nih.gov/pubmed/32174795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.39779
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