Centrioles control the capacity, but not the specificity, of cytotoxic T cell killing

Immunological synapse formation between cytotoxic T lymphocytes (CTLs) and the target cells they aim to destroy is accompanied by reorientation of the CTL centrosome to a position beneath the synaptic membrane. Centrosome polarization is thought to enhance the potency and specificity of killing by d...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Tamzalit, Fella, Tran, Diana, Jin, Weiyang, Boyko, Vitaly, Bazzi, Hisham, Kepecs, Ariella, Kam, Lance C., Anderson, Kathryn V., Huse, Morgan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049148/
https://ncbi.nlm.nih.gov/pubmed/32041868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913220117
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