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Skeletal Toxicity Resulting from Exposure of Growing Male Rats to Coplanar PCB 126 is Associated with Disruption of Calcium Homeostasis and the GH-IGF-1 Axis and Direct Effects on Bone Formation
Skeletal toxicity has been reported following exposure to polychlorinated biphenyl (PCB) mixtures. However, molecular mechanisms remain poorly understood. We exposed groups of male 4-5 week-old Sprague-Dawley rats to 3,3’, 4, 4’, 5-pentachlorobiphenyl (PCB 126), a dioxin-like coplanar PCB congener b...
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| Publicado no: | Arch Toxicol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7047627/ https://ncbi.nlm.nih.gov/pubmed/31820026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-019-02645-w |
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