Computational Mechanisms of Effort and Reward Decisions in Patients With Depression and Their Association With Relapse After Antidepressant Discontinuation

IMPORTANCE: Nearly 1 in 3 patients with major depressive disorder who respond to antidepressants relapse within 6 months of treatment discontinuation. No predictors of relapse exist to guide clinical decision-making in this scenario. OBJECTIVES: To establish whether the decision to invest effort for...

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Detalhes bibliográficos
Publicado no:JAMA Psychiatry
Main Authors: Berwian, Isabel M., Wenzel, Julia G., Collins, Anne G. E., Seifritz, Erich, Stephan, Klaas E., Walter, Henrik, Huys, Quentin J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2020
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042923/
https://ncbi.nlm.nih.gov/pubmed/32074255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2019.4971
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