FOXC2 Promotes Oxaliplatin Resistance by Inducing Epithelial-Mesenchymal Transition via MAPK/ERK Signaling in Colorectal Cancer

BACKGROUND: Chemoresistance is a major obstacle to improving the survival rate of colorectal cancer (CRC) patients. Forkhead box protein C2 (FOXC2), a member of the forkhead box (Fox) transcription factor family, is reported to be an important regulator of epithelial-to-mesenchymal transition (EMT)...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Chen, Yihong, Deng, Ganlu, Fu, Yaojie, Han, Ying, Guo, Cao, Yin, Ling, Cai, Changjing, Shen, Hong, Wu, Shaobin, Zeng, Shan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041600/
https://ncbi.nlm.nih.gov/pubmed/32110058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S241367
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