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Von Hippel–Lindau tumor suppressor (VHL) stimulates TOR signaling by interacting with phosphoinositide 3-kinase (PI3K)

Cell growth is positively controlled by the phosphoinositide 3-kinase (PI3K)–target of rapamycin (TOR) signaling pathway under conditions of abundant growth factors and nutrients. To discover additional mechanisms that regulate cell growth, here we performed RNAi-based mosaic analyses in the Drosoph...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Hwang, Sun-Hong, Bang, Sunhoe, Kim, Wonho, Chung, Jongkyeong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039557/
https://ncbi.nlm.nih.gov/pubmed/31959630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011596
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