Co-expression network analysis reveals the pivotal role of mitochondrial dysfunction and interferon signature in juvenile dermatomyositis

BACKGROUND: Juvenile dermatomyositis (JDM) is an immune-mediated disease characterized by chronic organ inflammation. The pathogenic mechanisms remain ill-defined. METHODS: Raw microarray data of JDM were obtained from the gene expression omnibus (GEO) database. Based on the GSE3307 dataset with 39...

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Bibliographische Detailangaben
Veröffentlicht in:PeerJ
Hauptverfasser: Zhong, Danli, Wu, Chanyuan, Bai, Jingjing, Xu, Dong, Zeng, Xiaofeng, Wang, Qian
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2020
Schlagworte:
Bioinformatics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034382/
https://ncbi.nlm.nih.gov/pubmed/32110496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.8611
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