Seizures induce obstructive apnea in DBA/2J audiogenic seizure-prone mice: lifesaving impact of tracheal implants

The mechanism(s) for sudden death in epilepsy (SUDEP) remain(s) unknown, but seizure spread to brainstem areas serving autonomic and respiratory function is critical. In a rat model, we established a mechanism for SUDEP that involves seizure-induced laryngospasm and obstructive apnea lasting until r...

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Bibliographic Details
Published in:Epilepsia
Main Authors: Irizarry, Rachel, Sukato, Daniel, Kollmar, Richard, Schild, Samuel, Silverman, Joshua, Sundaram, Krishnamurthi, Stephenson, Stacy, Stewart, Mark
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033013/
https://ncbi.nlm.nih.gov/pubmed/31944280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.16431
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