Targeted deep sequencing revealed variants in cell-free DNA of hormone receptor-positive metastatic breast cancer patients

Cell-free DNA (cfDNA) is described to mirror intratumoral heterogeneity and gives insight about clonal evolution for improved therapeutic decisions. We sequenced cfDNA of a hormone receptor-positive, HER2-negative metastatic breast cancer (MBC) cohort with a high coverage to examine the prevalence a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Mol Life Sci
Prif Awduron: Keup, Corinna, Benyaa, Karim, Hauch, Siegfried, Sprenger-Haussels, Markus, Tewes, Mitra, Mach, Pawel, Bittner, Ann-Kathrin, Kimmig, Rainer, Hahn, Peter, Kasimir-Bauer, Sabine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2019
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010653/
https://ncbi.nlm.nih.gov/pubmed/31254045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03189-z
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