Silica Perturbs Primary Cilia and Causes Myofibroblast Differentiation during Silicosis by Reduction of the KIF3A-Repressor GLI3 Complex

The purpose of this study was to determine the effects of Kinesin family member 3A (KIF3A) on primary cilia and myofibroblast differentiation during silicosis by regulating Sonic hedgehog (SHH) signalling. Methods: Changes in primary cilia during silicosis and myofibroblast differentiation were dete...

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Detalles Bibliográficos
Publicado en:Theranostics
Main Authors: Li, Shifeng, Wei, Zhongqiu, Li, Gengxu, Zhang, Qiaodan, Niu, Siyu, Xu, Dingjie, Mao, Na, Chen, Si, Gao, Xuemin, Cai, Wenchen, Zhu, Ying, Zhang, Guizhen, Li, Dan, Yi, Xue, Yang, Fang, Xu, Hong
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993221/
https://ncbi.nlm.nih.gov/pubmed/32042332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.37049
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