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Acute myeloid leukemia with inv(16)(p13.1q22) and deletion of the 5’MYH11/3’CBFB gene fusion: a report of two cases and literature review

BACKGROUND: Abnormalities of chromosome 16 are found in about 5–8% of acute myeloid leukemia (AML). The AML with inv(16)(p13.1q22) or t (16;16)(p13.1;q22) is associated with a high rate of complete remission (CR) and favorable overall survival (OS) when treated with high-dose Cytarabine. At the inve...

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Vydáno v:Mol Cytogenet
Hlavní autoři: Lv, Lili, Yu, Jingwei, Qi, Zhongxia
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990480/
https://ncbi.nlm.nih.gov/pubmed/32015759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-020-0474-9
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