Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells

How chromosome organization is related to genome function remains poorly understood. Cohesin, loop extrusion, and CCCTC-binding factor (CTCF) have been proposed to create topologically associating domains (TADs) to regulate gene expression. Here, we examine chromosome conformation in embryonic stem...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Rep
Päätekijät: Rhodes, James D.P., Feldmann, Angelika, Hernández-Rodríguez, Benjamín, Díaz, Noelia, Brown, Jill M., Fursova, Nadezda A., Blackledge, Neil P., Prathapan, Praveen, Dobrinic, Paula, Huseyin, Miles K., Szczurek, Aleksander, Kruse, Kai, Nasmyth, Kim A., Buckle, Veronica J., Vaquerizas, Juan M., Klose, Robert J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988126/
https://ncbi.nlm.nih.gov/pubmed/31968256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.12.057
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