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A novel mouse model of acute-on-chronic cholestatic alcoholic liver disease: A systems biology comparison with human alcoholic hepatitis

BACKGROUND: Alcohol-related liver disease is the main cause of liver-related mortality worldwide. The development of novel targeted therapies for patients with advanced forms (i.e., alcoholic hepatitis, AH) is hampered by the lack of suitable animal models. Here, we developed a novel mouse model of...

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Vydáno v:Alcohol Clin Exp Res
Hlavní autoři: Furuya, Shinji, Argemi, Josepmaria, Uehara, Takeki, Katou, Yuuki, Fouts, Derrick E., Schnabl, Bernd, Dubuquoy, Laurent, Belorkar, Abha, Vadigepalli, Rajanikanth, Kono, Hiroshi, Bataller, Ramon, Rusyn, Ivan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980964/
https://ncbi.nlm.nih.gov/pubmed/31710124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14234
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