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Flagellin adjuvanted F1/V subunit plague vaccine induces T cell and functional antibody responses with unique gene signatures

Yersinia pestis, the cause of plague, could be weaponized. Unfortunately, development of new vaccines is limited by lack of correlates of protection. We used pre- and post-vaccination sera and peripheral blood mononuclear cells from a flagellin adjuvanted F1/V vaccine trial to evaluate for protectiv...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:NPJ Vaccines
Egile Nagusiak: Hamzabegovic, Fahreta, Goll, Johannes B., Hooper, William F., Frey, Sharon, Gelber, Casey E., Abate, Getahun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978331/
https://ncbi.nlm.nih.gov/pubmed/31993217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0156-y
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