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Flagellin adjuvanted F1/V subunit plague vaccine induces T cell and functional antibody responses with unique gene signatures

Yersinia pestis, the cause of plague, could be weaponized. Unfortunately, development of new vaccines is limited by lack of correlates of protection. We used pre- and post-vaccination sera and peripheral blood mononuclear cells from a flagellin adjuvanted F1/V vaccine trial to evaluate for protectiv...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Hamzabegovic, Fahreta, Goll, Johannes B., Hooper, William F., Frey, Sharon, Gelber, Casey E., Abate, Getahun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978331/
https://ncbi.nlm.nih.gov/pubmed/31993217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0156-y
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