Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis

BACKGROUND: Colon cancer stem cells (CSCs), considered responsible for tumor initiation and cancer relapse, are constantly exposed to regulatory cues emanating from neighboring cells present in the tumor microenvironment. Among these cells are enteric glial cells (EGCs) that are potent regulators of...

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Vydáno v:EBioMedicine
Hlavní autoři: Valès, Simon, Bacola, Gregory, Biraud, Mandy, Touvron, Mélissa, Bessard, Anne, Geraldo, Fanny, Dougherty, Kelsie A., Lashani, Shaian, Bossard, Céline, Flamant, Mathurin, Duchalais, Emilie, Marionneau-Lambot, Séverine, Oullier, Thibauld, Oliver, Lisa, Neunlist, Michel, Vallette, François M., Van Landeghem, Laurianne
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945247/
https://ncbi.nlm.nih.gov/pubmed/31662289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.045
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