Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis

BACKGROUND: Colon cancer stem cells (CSCs), considered responsible for tumor initiation and cancer relapse, are constantly exposed to regulatory cues emanating from neighboring cells present in the tumor microenvironment. Among these cells are enteric glial cells (EGCs) that are potent regulators of...

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Udgivet i:EBioMedicine
Main Authors: Valès, Simon, Bacola, Gregory, Biraud, Mandy, Touvron, Mélissa, Bessard, Anne, Geraldo, Fanny, Dougherty, Kelsie A., Lashani, Shaian, Bossard, Céline, Flamant, Mathurin, Duchalais, Emilie, Marionneau-Lambot, Séverine, Oullier, Thibauld, Oliver, Lisa, Neunlist, Michel, Vallette, François M., Van Landeghem, Laurianne
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
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Research paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945247/
https://ncbi.nlm.nih.gov/pubmed/31662289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.045
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