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m(6)A Methylation of Precursor-miR-320/RUNX2 Controls Osteogenic Potential of Bone Marrow-Derived Mesenchymal Stem Cells

Methyltransferase-like 3 (METTL3) is the main enzyme for N(6)-methyladenosine (m(6)A)-based methylation of RNAs and it has been implicated in many biological and pathophysiological processes. In this study, we aimed to explore the potential involvement of METTL3 in osteoblast differentiation and dec...

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Détails bibliographiques
Publié dans:Mol Ther Nucleic Acids
Auteurs principaux: Yan, Gege, Yuan, Ye, He, Mingyu, Gong, Rui, Lei, Hong, Zhou, Hongbao, Wang, Wenbo, Du, Weijie, Ma, Tianshuai, Liu, Shenzhen, Xu, Zihang, Gao, Manqi, Yu, Meixi, Bian, Yu, Pang, Ping, Li, Xin, Yu, Shuting, Yang, Fan, Cai, Benzhi, Yang, Lei
Format: Artigo
Langue:Inglês
Publié: American Society of Gene & Cell Therapy 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940653/
https://ncbi.nlm.nih.gov/pubmed/31896070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.12.001
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