m(6)A Methylation of Precursor-miR-320/RUNX2 Controls Osteogenic Potential of Bone Marrow-Derived Mesenchymal Stem Cells

Methyltransferase-like 3 (METTL3) is the main enzyme for N(6)-methyladenosine (m(6)A)-based methylation of RNAs and it has been implicated in many biological and pathophysiological processes. In this study, we aimed to explore the potential involvement of METTL3 in osteoblast differentiation and dec...

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Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Yan, Gege, Yuan, Ye, He, Mingyu, Gong, Rui, Lei, Hong, Zhou, Hongbao, Wang, Wenbo, Du, Weijie, Ma, Tianshuai, Liu, Shenzhen, Xu, Zihang, Gao, Manqi, Yu, Meixi, Bian, Yu, Pang, Ping, Li, Xin, Yu, Shuting, Yang, Fan, Cai, Benzhi, Yang, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940653/
https://ncbi.nlm.nih.gov/pubmed/31896070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.12.001
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