Kinetic Modeling of Hyperpolarized Carbon-13 Pyruvate Metabolism in the Human Brain

Kinetic modeling of the in vivo pyruvate-to-lactate conversion is crucial to investigating aberrant cancer metabolism that demonstrates Warburg effect modifications. Non-invasive detection of alterations to metabolic flux might offer prognostic value and improve the monitoring of response to treatme...

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Udgivet i:IEEE Trans Med Imaging
Main Authors: Mammoli, Daniele, Gordon, Jeremy, Autry, Adam, Larson, Peder E. Z., Li, Yan, Chen, Hsin-Yu, Chung, Brian, Shin, Peter, Criekinge, Mark Van, Carvajal, Lucas, Slater, James B., Bok, Robert, Crane, Jason, Xu, Duan, Chang, Susan, Vigneron, Daniel B.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939147/
https://ncbi.nlm.nih.gov/pubmed/31283497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TMI.2019.2926437
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