Enhancer polymorphism rs10865710 associated with traumatic sepsis is a regulator of PPARG gene expression

BACKGROUND: Peroxisome proliferator-activated receptor gamma (PPARγ) is a major regulator in sepsis. Our previous study identified the enhancer polymorphism rs10865710C/G to be associated with susceptibility to sepsis in trauma patients. We performed two-stage cohort studies integrating biological e...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Crit Care
Main Authors: Lu, Hongxiang, Wen, Dalin, Sun, Jianhui, Zeng, Ling, Du, Juan, Du, Dingyuan, Zhang, Lianyang, Deng, Jin, Jiang, Jianxin, Zhang, Anqiang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938012/
https://ncbi.nlm.nih.gov/pubmed/31888703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-019-2707-z
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