Oscillatory cAMP signaling rapidly alters H3K4 methylation

Epigenetic variation reflects the impact of a dynamic environment on chromatin. However, it remains elusive how environmental factors influence epigenetic events. Here, we show that G protein–coupled receptors (GPCRs) alter H3K4 methylation via oscillatory intracellular cAMP. Activation of Gs-couple...

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Publicado en:Life Sci Alliance
Autores principales: Huff, Tyler C, Camarena, Vladimir, Sant, David W, Wilkes, Zachary, Van Booven, Derek, Aron, Allegra T, Muir, Ryan K, Renslo, Adam R, Chang, Christopher J, Monje, Paula V, Wang, Gaofeng
Formato: Artigo
Lenguaje:Inglês
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935296/
https://ncbi.nlm.nih.gov/pubmed/31882444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900529
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