Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Ercolano, Giuseppe, De Cicco, Paola, Rubino, Valentina, Terrazzano, Giuseppe, Ruggiero, Giuseppina, Carriero, Roberta, Kunderfranco, Paolo, Ianaro, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915044/
https://ncbi.nlm.nih.gov/pubmed/31920649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01456
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