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Hypoxia and EGF Stimulation Regulate VEGF Expression in Human Glioblastoma Multiforme (GBM) Cells by Differential Regulation of the PI3K/Rho-GTPase and MAPK Pathways

Glioblastoma multiforme (GBM) is one of the most common and deadly cancers of the central nervous system (CNS). It is characterized by the presence of hypoxic regions, especially in the core, leading to an increase in vascularity. This increased vascularization is driven by the expression of the maj...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Nicolas, Samer, Abdellatef, Sandra, Haddad, Maria Al, Fakhoury, Isabelle, El-Sibai, Mirvat
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912653/
https://ncbi.nlm.nih.gov/pubmed/31698752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111397
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