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One-step radiosynthesis of the MCTs imaging agent [(18)F]FACH by aliphatic (18)F-labelling of a methylsulfonate precursor containing an unprotected carboxylic acid group

Monocarboxylate transporters 1 and 4 (MCT1 and MCT4) are involved in tumour development and progression. Their level of expression is particularly upregulated in glycolytic cancer cells and accordingly MCTs are considered as promising drug targets for treatment of a variety of human cancers. The non...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sadeghzadeh, Masoud, Moldovan, Rareş-Petru, Teodoro, Rodrigo, Brust, Peter, Wenzel, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906299/
https://ncbi.nlm.nih.gov/pubmed/31827199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55354-w
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