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Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis

Epithelial ovarian cancer (EOC) is the deadliest female malignancy. The Wnt/β-catenin pathway plays critical roles in regulating embryonic development and physiological processes. This pathway is tightly regulated to ensure its proper activity. In the absence of Wnt ligands, β-catenin is degraded by...

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Bibliografiske detaljer
Udgivet i:J Ovarian Res
Main Authors: Nguyen, Vu Hong Loan, Hough, Rebecca, Bernaudo, Stefanie, Peng, Chun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905042/
https://ncbi.nlm.nih.gov/pubmed/31829231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-019-0596-z
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