IL-1Ra protects hematopoietic cells from chemotoxicity through p53-induced quiescence

The protection of constantly proliferating gut epithelia and hematopoietic tissues from cytotoxicity could improve conventional chemotherapy efficacy and widen its therapeutic window. Previously, we reported that, in mouse models, pretreatment of recombinant human IL-1 receptor antagonist (rhIL-1Ra)...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:FASEB J
Hlavní autoři: Ye, Hao, Qian, Lan, Zhu, Shunying, Deng, Shaorong, Wang, Xia, Zhu, Jiang, Chan, Gerald L., Yu, Yan, Han, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902709/
https://ncbi.nlm.nih.gov/pubmed/31373847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900788RR
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky