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IL-1Ra protects hematopoietic cells from chemotoxicity through p53-induced quiescence

The protection of constantly proliferating gut epithelia and hematopoietic tissues from cytotoxicity could improve conventional chemotherapy efficacy and widen its therapeutic window. Previously, we reported that, in mouse models, pretreatment of recombinant human IL-1 receptor antagonist (rhIL-1Ra)...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Ye, Hao, Qian, Lan, Zhu, Shunying, Deng, Shaorong, Wang, Xia, Zhu, Jiang, Chan, Gerald L., Yu, Yan, Han, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902709/
https://ncbi.nlm.nih.gov/pubmed/31373847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900788RR
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