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Toscana virus non-structural protein NSs acts as E3 ubiquitin ligase promoting RIG-I degradation
It is known that the non-structural protein (NSs) of Toscana virus (TOSV), an emergent sandfly-borne virus causing meningitis or more severe central nervous system injuries in humans, exerts its function triggering RIG-I for degradation in a proteasome-dependent manner, thus breaking off the IFN-β p...
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| Veröffentlicht in: | PLoS Pathog |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6901176/ https://ncbi.nlm.nih.gov/pubmed/31815967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008186 |
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