Functional cytochrome P450 1A enzymes are induced in mouse and human islets following pollutant exposure

AIMS/HYPOTHESIS: Exposure to environmental pollution has been consistently linked to diabetes incidence in humans, but the potential causative mechanisms remain unclear. Given the critical role of regulated insulin secretion in maintaining glucose homeostasis, environmental chemicals that reach the...

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Опубликовано в: :Diabetologia
Главные авторы: Ibrahim, Muna, MacFarlane, Erin M., Matteo, Geronimo, Hoyeck, Myriam P., Rick, Kayleigh R. C., Farokhi, Salar, Copley, Catherine M., O’Dwyer, Shannon, Bruin, Jennifer E.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890627/
https://ncbi.nlm.nih.gov/pubmed/31776611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-019-05035-0
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