Relationship between diffusion capacity and small airway abnormality in COPDGene

ABSTRACT: Impaired single breath carbon monoxide diffusing capacity (DLCO) is associated with emphysema. Small airways disease (SAD) may be a precursor lesion to emphysema, but the relationship between SAD and DLCO is undescribed. We hypothesized that in mild COPD, functional SAD (fSAD) defined by c...

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Pubblicato in:Respir Res
Autori principali: Criner, Rachel N., Hatt, Charles R., Galbán, Craig J., Kazerooni, Ella A., Lynch, David A., McCormack, Meredith C., Casaburi, Richard, MacIntyre, Neil R., Make, Barry J., Martinez, Fernando J., Labaki, Wassim W., Curtis, Jeffrey L., Han, Mei Lan K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Letter to the Editor
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889734/
https://ncbi.nlm.nih.gov/pubmed/31791337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1237-1
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