Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR

BACKGROUND: In phylogenetically diverse organisms, the 5′ ends of a subset of mRNAs are trans-spliced with a spliced leader (SL) RNA. The functions of SL trans-splicing, however, remain largely enigmatic. RESULTS: We quantified translation genome-wide in the marine chordate, Oikopleura dioica, under...

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Pubblicato in:BMC Genomics
Autori principali: Danks, Gemma B., Galbiati, Heloisa, Raasholm, Martina, Torres Cleuren, Yamila N., Valen, Eivind, Navratilova, Pavla, Thompson, Eric M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883708/
https://ncbi.nlm.nih.gov/pubmed/31783727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6277-x
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