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Influenza viruses that require 10 genomic segments as antiviral therapeutics
Influenza A viruses (IAVs) encode their genome across eight, negative sense RNA segments. During viral assembly, the failure to package all eight segments, or packaging a mutated segment, renders the resulting virion incompletely infectious. It is known that the accumulation of these defective parti...
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| Veröffentlicht in: | PLoS Pathog |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881065/ https://ncbi.nlm.nih.gov/pubmed/31730644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008098 |
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