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Influenza viruses that require 10 genomic segments as antiviral therapeutics

Influenza A viruses (IAVs) encode their genome across eight, negative sense RNA segments. During viral assembly, the failure to package all eight segments, or packaging a mutated segment, renders the resulting virion incompletely infectious. It is known that the accumulation of these defective parti...

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Foilsithe in:PLoS Pathog
Main Authors: Harding, Alfred T., Haas, Griffin D., Chambers, Benjamin S., Heaton, Nicholas S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881065/
https://ncbi.nlm.nih.gov/pubmed/31730644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008098
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