Monitoring method for transgene expression in target tissue by blood sampling

In this study, we have developed a novel method to monitor transgene expression in tissues by blood sampling. We administered plasmid DNA (pDNA) encoding non-secretory form of firefly luciferase as a reporter gene and pDNA encoding secretable Gaussia princeps luciferase as a monitor gene simultaneou...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biotechnol Rep (Amst)
Hauptverfasser: Kinoshita, Eriko, Fumoto, Shintaro, Hori, Yuta, Yoshikawa, Naoki, Miyamoto, Hirotaka, Sasaki, Hitoshi, Nakamura, Junzo, Tanaka, Takashi, Nishida, Koyo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880019/
https://ncbi.nlm.nih.gov/pubmed/31788440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2019.e00401
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