A clinically relevant murine model unmasks a “two‐hit” mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant

Reactivation of latent cytomegalovirus remains an important complication after transplant. Although immunosuppression (IS) has been implicated as a primary cause, we have previously shown that the implantation response of a kidney allograft can lead to early transcriptional activation of latent muri...

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Veröffentlicht in:Am J Transplant
Hauptverfasser: Zhang, Zheng, Qiu, Longhui, Yan, Shixian, Wang, Jiao-Jing, Thomas, Paul M., Kandpal, Manoj, Zhao, Lihui, Iovane, Andre, Liu, Xue-feng, Thorp, Edward B., Chen, Qing, Hummel, Mary, Kanwar, Yashpal S., Abecassis, Michael M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873708/
https://ncbi.nlm.nih.gov/pubmed/30947382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15376
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