Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases

The widespread occurrence of repetitive stretches of DNA in genomes of organisms across the tree of life imposes fundamental challenges for sequencing, genome assembly, and automated annotation of genes and proteins. This multi-level problem can lead to errors in genome and protein databases that ar...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Tørresen, Ole K, Star, Bastiaan, Mier, Pablo, Andrade-Navarro, Miguel A, Bateman, Alex, Jarnot, Patryk, Gruca, Aleksandra, Grynberg, Marcin, Kajava, Andrey V, Promponas, Vasilis J, Anisimova, Maria, Jakobsen, Kjetill S, Linke, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Survey and Summary
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868369/
https://ncbi.nlm.nih.gov/pubmed/31584084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz841
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