Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases

The widespread occurrence of repetitive stretches of DNA in genomes of organisms across the tree of life imposes fundamental challenges for sequencing, genome assembly, and automated annotation of genes and proteins. This multi-level problem can lead to errors in genome and protein databases that ar...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Tørresen, Ole K, Star, Bastiaan, Mier, Pablo, Andrade-Navarro, Miguel A, Bateman, Alex, Jarnot, Patryk, Gruca, Aleksandra, Grynberg, Marcin, Kajava, Andrey V, Promponas, Vasilis J, Anisimova, Maria, Jakobsen, Kjetill S, Linke, Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868369/
https://ncbi.nlm.nih.gov/pubmed/31584084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz841
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