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Cumulative Toxicity in Targeted Therapies: What to Expect at the Recommended Phase II Dose

BACKGROUND: In the era of molecularly targeted agents (MTAs), it is recommended to account for toxicity over several cycles to identify the recommended phase II dose (RP2D). We investigated the relationship between the risk of toxicity at cycle 1 and the cumulative incidence of toxicity over subsequ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Natl Cancer Inst
Egile Nagusiak: Altzerinakou, Maria-Athina, Collette, Laurence, Paoletti, Xavier
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855968/
https://ncbi.nlm.nih.gov/pubmed/30838405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz024
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