Increased Hemoglobin Oxygen Affinity With 5-Hydroxymethylfurfural Supports Cardiac Function During Severe Hypoxia

Acclimatization to hypoxia or high altitude involves physiological adaptation processes, to influence oxygen (O(2)) transport and utilization. Several natural products, including aromatic aldehydes and isothiocyanates stabilize the R-state of hemoglobin (Hb), increasing Hb-O(2) affinity and Hb-O(2)...

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Publicado no:Front Physiol
Main Authors: Lucas, Alfredo, Ao-ieong, Eilleen S. Y., Williams, Alexander T., Jani, Vivek P., Muller, Cynthia R., Yalcin, Ozlem, Cabrales, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831744/
https://ncbi.nlm.nih.gov/pubmed/31736778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01350
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