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Discovering long noncoding RNA predictors of anticancer drug sensitivity beyond protein-coding genes

Large-scale cancer cell line screens have identified thousands of protein-coding genes (PCGs) as biomarkers of anticancer drug response. However, systematic evaluation of long noncoding RNAs (lncRNAs) as pharmacogenomic biomarkers has so far proven challenging. Here, we study the contribution of lnc...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Nath, Aritro, Lau, Eunice Y. T., Lee, Adam M., Geeleher, Paul, Cho, William C. S., Huang, R. Stephanie
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825320/
https://ncbi.nlm.nih.gov/pubmed/31548386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909998116
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