Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation

The nucleus pulposus (NP) cells adapt to their physiologically hyperosmotic microenvironment through Tonicity-responsive enhancer binding protein (TonEBP/nuclear factor of activated T-cell5 [NFAT5])-mediated osmoregulation. Primary cilia in different organs serve diverse roles including osmosensing,...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Choi, Hyowon, Madhu, Vedavathi, Shapiro, Irving M., Risbud, Makarand V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820757/
https://ncbi.nlm.nih.gov/pubmed/31664118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51939-7
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