Interaction Effects between Doxorubicin and Hernandezine on the Pharmacokinetics by Liquid Chromatography Coupled with Mass Spectrometry

Doxorubicin (DOX) is an effective anti-tumor drug widely used in clinics. Hernandezine (HER), isolated from a Chinese medicinal herb, has a selective inhibitory effect on DOX multidrug resistance, making DOX more effective in treating cancer. The aim of this study was to investigate the effect of th...

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Udgivet i:Molecules
Main Authors: Song, Yang, Zhang, Yuan, Zhang, Wei-Peng, Zhang, Bao-Zhen, Wang, Ke-Fei, Feng, Xue-Song
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804073/
https://ncbi.nlm.nih.gov/pubmed/31597294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24193622
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