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2464 Sexual dimorphism in a mouse model of syndromic thoracic aortic aneurysm

OBJECTIVES/SPECIFIC AIMS: Pre-clinical and clinical observations have noted that increased aortic dilation is associated with male sex. Using an experimental model of severe, syndromic thoracic aortic aneurysms, we quantify aortic dilation and elastin stability in male Versus female mice. METHODS/ST...

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Detalhes bibliográficos
Publicado no:J Clin Transl Sci
Main Authors: Chen, Zheying, Daugherty, Alan, Sheppard, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799199/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.121
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