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Synthetic presentation of noncanonical Wnt5a motif promotes mechanosensing-dependent differentiation of stem cells and regeneration

Noncanonical Wnt signaling in stem cells is essential to numerous developmental events. However, no prior studies have capitalized on the osteoinductive potential of noncanonical Wnt ligands to functionalize biomaterials in enhancing the osteogenesis and associated skeleton formation. Here, we inves...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Li, Rui, Lin, Sien, Zhu, Meiling, Deng, Yingrui, Chen, Xiaoyu, Wei, Kongchang, Xu, Jianbin, Li, Gang, Bian, Liming
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795506/
https://ncbi.nlm.nih.gov/pubmed/31663014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw3896
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