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The Increase of the Magnitude of Spontaneous Viral Blips in Some Participants of Phase II Clinical Trial of Therapeutic Optimized HIV DNA Vaccine Candidate

We developed a candidate DNA vaccine called “DNA-4”consisting of 4 plasmid DNAs encoding Nef, Gag, Pol(rt), and gp140 HIV-1 proteins. The vaccine was found to be safe and immunogenic in a phase I clinical trial. Here we present the results of a phase II clinical trial of “DNA-4”. This was a multicen...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Akulova, Ekaterina, Murashev, Boris, Verevochkin, Sergey, Masharsky, Alexey, Al-Shekhadat, Ruslan, Poddubnyy, Valeriy, Zozulya, Olga, Vostokova, Natalia, Kozlov, Andrei P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789887/
https://ncbi.nlm.nih.gov/pubmed/31434305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7030092
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