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Tetanic Stimulation Leads to Increased Accumulation of Ca(2+)/Calmodulin-Dependent Protein Kinase II via Dendritic Protein Synthesis in Hippocampal Neurons

mRNA for the α-subunit of CaMKII is abundant in dendrites of neurons in the forebrain (Steward, 1997). Here we show that tetanic stimulation of the Schaffer collateral pathway causes an increase in the concentration of α-CaMKII in the dendrites of postsynaptic neurons. The increase is blocked by ani...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Ouyang, Yannan, Rosenstein, Alan, Kreiman, Gabriel, Schuman, Erin M., Kennedy, Mary B.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782482/
https://ncbi.nlm.nih.gov/pubmed/10479685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-18-07823.1999
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